Description

Formulations:

• Cefotaxime Vial: Available in multiple strengths, including 250mg, 500mg, and 1000mg, our vials contain a sterile powder for reconstitution, ensuring optimal efficacy and convenience for healthcare providers.

Indications:

• Our Cefotaxime Vial is indicated for the treatment of various bacterial infections caused by susceptible organisms, including:
  • Lower respiratory tract infections, such as pneumonia
  • Urinary tract infections, including complicated urinary tract infections (cUTIs) and pyelonephritis
  • Intra-abdominal infections, such as peritonitis
  • Gynecological infections, including pelvic inflammatory disease (PID)
  • Skin and soft tissue infections, including cellulitis and wound infections
  • Septicemia
  • Meningitis

Pharmacokinetics:

• Absorption: Cefotaxime is administered intravenously and achieves rapid and complete absorption into the systemic circulation.
• Distribution: The drug distributes widely into various body tissues and fluids, including the lungs, kidneys, liver, and cerebrospinal fluid.
• Metabolism: Cefotaxime undergoes minimal metabolism in the liver, with approximately 80% of the unchanged drug excreted in the urine within 24 hours.
• Elimination: The elimination half-life of cefotaxime is approximately 1-1.5 hours in adults with normal renal function.

Pharmacodynamics:

• Cefotaxime exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, leading to cell death.

Usage:

• Our Cefotaxime Vial is intended for intravenous administration by healthcare professionals trained in the proper handling and reconstitution of injectable medications.

Dosage:

• The dosage of Cefotaxime Vial varies depending on the type and severity of the infection, as well as the patient’s age, weight, and renal function.
• Dosage adjustments may be necessary in patients with impaired renal function to prevent drug accumulation and toxicity.

Side Effects:

• Common side effects of Cefotaxime may include:
  • Nausea and vomiting
  • Diarrhea
  • Injection site reactions, such as pain and inflammation
• Serious side effects such as hypersensitivity reactions and superinfections may occur, although they are rare.

Experience the effectiveness and reliability of AIT Pharmaceuticals Division’s Cefotaxime Vial Range in the treatment of bacterial infections. For more information, please contact us.