Alliance of Infinity Trade
Artemether + Lumefantrine
Introducing AIT Pharmaceuticals Division’s Artemether + Lumefantrine Range
At AIT Pharmaceuticals Division, we are committed to providing innovative pharmaceutical solutions to combat infectious diseases worldwide. Our Artemether + Lumefantrine Range offers a potent combination therapy for the treatment of uncomplicated malaria caused by Plasmodium falciparum.
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Drug Classification:
Artemether + Lumefantrine is classified as an antimalarial agent. It combines two active ingredients, Artemether and Lumefantrine, which work synergistically to eradicate malaria parasites from the body.
Formulations:
- Artemether + Lumefantrine Dry Suspension:
- Strength: Each 5ml of suspension contains 30 mg Artemether and 180 mg Lumefantrine.
- Product Form: Dry suspension for oral administration.
- Packing Specifications: Supplied in a bottle containing 60ml of suspension.
- Artemether + Lumefantrine Tablets:
- Strengths:
- 20 mg Artemether + 120 mg Lumefantrine tablets (16’s)
- 40 mg Artemether + 240 mg Lumefantrine tablets (8’s)
- 80mg Artemether + 480mg Lumefantrine tablets (4’s)
- Product Form: Oral tablets for convenient dosing.
- Packing Specifications: Packaged in blister packs containing the specified number of tablets.
- Strengths:
Indications:
Artemether + Lumefantrine is indicated for the treatment of uncomplicated malaria caused by Plasmodium falciparum, including multi-drug resistant strains. It is not recommended for prophylaxis or treatment of severe malaria.
Usage:
- The oral suspension should be reconstituted according to the instructions provided before administration.
- Tablets should be swallowed whole with water and may be taken with or without food.
- Patients should complete the full course of treatment as prescribed by their healthcare provider, even if symptoms improve before completion.
Dosage:
- Dosage regimens may vary based on factors such as the patient’s age, weight, and severity of infection.
- The recommended dosage for Artemether + Lumefantrine is typically based on body weight and administered twice daily for three days.
- The specific dosage for each strength of tablet or suspension should be determined by a qualified healthcare professional.
Pharmacokinetics:
- Artemether is rapidly metabolized to its active metabolite dihydroartemisinin, which has a rapid onset of action against malaria parasites.
- Lumefantrine is absorbed slowly and metabolized in the liver to its active metabolite desbutyl-lumefantrine, which contributes to the prolonged antimalarial activity.
Pharmacodynamics:
- Artemether acts rapidly to kill malaria parasites, particularly the early stages of the parasite’s life cycle, including the ring and trophozoite stages.
- Lumefantrine has a longer half-life and provides sustained antimalarial activity, preventing recrudescence of the infection and reducing the risk of treatment failure.
Side Effects:
- Common side effects of Artemether + Lumefantrine may include nausea, vomiting, diarrhea, abdominal pain, and headache.
- Rare but serious side effects may include cardiac arrhythmias, hypersensitivity reactions, and hepatic dysfunction.
- Patients should be monitored for any adverse reactions during treatment, and healthcare providers should be informed of any concerning symptoms.
Experience the efficacy and reliability of AIT Pharmaceuticals Division’s Artemether + Lumefantrine Range in the fight against malaria. For more information, please contact us. We are dedicated to advancing global health through innovative pharmaceutical solutions.
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