Description

Drug Classification:

Ziprasidone, as a hydrochloride monohydrate, belongs to the class of drugs known as atypical antipsychotics. This medication is specifically designed to treat symptoms of schizophrenia and bipolar disorder, providing relief from psychotic symptoms, mood disturbances, and other related conditions.

Formulations:

• Ziprasidone Capsules:
  • Strengths: Available in formulations containing 40mg and 60mg of ziprasidone.
  • Product Form: Oral capsules for convenient administration.
  • Packing Specs: Each pack contains 14 capsules.

Indications:

Ziprasidone Capsules are indicated for the treatment of the following conditions:

• Schizophrenia: This medication is effective in managing the positive symptoms (e.g., hallucinations, delusions) and negative symptoms (e.g., social withdrawal, apathy) associated with schizophrenia.
• Bipolar Disorder: Ziprasidone is also indicated for the treatment of acute manic or mixed episodes associated with bipolar I disorder, providing stabilization of mood and prevention of relapse.

Usage:

• Ziprasidone Capsules should be taken orally, swallowed whole with water, with or without food.
• It is important to adhere to the prescribed dosage and dosing schedule as directed by a healthcare professional.
• Patients should not discontinue this medication abruptly, as this may lead to withdrawal symptoms or disease recurrence. Any changes in dosage or treatment plan should be discussed with a healthcare provider.

Dosage:

• The recommended starting dose of Ziprasidone Capsules varies depending on the individual’s condition and previous treatment history.
• Dosage adjustments may be made based on clinical response and tolerability, under the guidance of a healthcare professional.

Pharmacokinetics:

• Ziprasidone is rapidly absorbed after oral administration, with peak plasma concentrations achieved within 6 to 8 hours.
• The medication undergoes extensive hepatic metabolism, primarily via the cytochrome P450 enzyme system, leading to the formation of metabolites that are excreted primarily in the urine and feces.

Pharmacodynamics:

• Ziprasidone exerts its therapeutic effects through its antagonism of dopamine and serotonin receptors in the central nervous system.
• By blocking dopamine D2 and serotonin 5-HT2A receptors, ziprasidone helps to alleviate psychotic symptoms, stabilize mood, and improve overall functioning in individuals with schizophrenia and bipolar disorder.

Side Effects:

• Common side effects associated with Ziprasidone Capsules may include drowsiness, dizziness, headache, nausea, and constipation.
• Less common but potentially serious side effects may include extrapyramidal symptoms, metabolic disturbances, and QT prolongation.
• Patients should be monitored closely for adverse reactions, and any concerning symptoms should be reported to a healthcare provider promptly.

Trust in the efficacy and safety of Ziprasidone Capsules from AIT Pharmaceuticals Division. Whether you are managing schizophrenia or bipolar disorder, our product offers a comprehensive treatment approach to help you achieve symptom control and improve your quality of life. For more information, please visit our website or consult your healthcare provider.