Description

Pharmacokinetics:

Cholecalciferol is absorbed in the small intestine and undergoes hydroxylation in the liver to form calcifediol (25-hydroxyvitamin D). Calcifediol is further metabolized in the kidneys to its biologically active form, calcitriol (1,25-dihydroxyvitamin D). The half-life of cholecalciferol varies but is generally around 2 to 3 weeks.

Pharmacodynamics:

Cholecalciferol plays a crucial role in maintaining calcium and phosphate homeostasis, essential for bone mineralization and skeletal health. It also modulates immune function, promotes muscle strength, and regulates various cellular processes throughout the body.

Drug Classification:

Cholecalciferol is classified as a vitamin supplement, specifically vitamin D3.

Formulations:

• Injection: 5mg liquid ampules

Indications:

AIT’s Cholecalciferol Range is indicated for the prevention and treatment of vitamin D deficiency, osteoporosis, and hypocalcemia. It is also recommended for use in individuals at risk of inadequate sun exposure or those with conditions impairing vitamin D absorption.

Usage:

Cholecalciferol injections are administered intramuscularly under the supervision of a healthcare professional. The frequency and dosage regimen depend on the individual’s age, medical condition, and severity of vitamin D deficiency. Consult a healthcare provider for personalized dosing recommendations.

Dosage:

The recommended dosage of Cholecalciferol varies depending on the indication and severity of deficiency. Standard dosing regimens may include a loading dose followed by maintenance therapy. Dosage adjustments may be necessary in certain populations, such as pregnant women or individuals with malabsorption disorders.

Side Effects:

Side effects of Cholecalciferol injections are rare but may include hypercalcemia, hypercalciuria, and vitamin D toxicity. Adverse reactions such as nausea, vomiting, and constipation may occur at high doses. Monitor serum calcium levels regularly and adjust dosage accordingly to minimize the risk of adverse effects.

Experience the benefits of vitamin D supplementation with AIT Pharmaceuticals Division’s Cholecalciferol Range. Trust in our commitment to quality and efficacy for optimal bone health and overall vitality.