Description

Pharmacokinetics:

Polyethylene Glycol (PEG) and Propylene Glycol (PG) are widely used pharmaceutical excipients with minimal systemic absorption when administered topically. PEG is a water-soluble polymer that functions as a lubricant and humectant, while PG is a solvent and vehicle that enhances the solubility and stability of active ingredients. Upon ocular administration, these agents provide moisturizing and lubricating effects, promoting comfort and hydration of the ocular surface.

Pharmacodynamics:

Polyethylene Glycol and Propylene Glycol exert their pharmacodynamic effects primarily by hydrating and lubricating the ocular surface. PEG forms a protective layer over the cornea and conjunctiva, reducing friction and discomfort associated with dry eye conditions. PG enhances the penetration and distribution of active ingredients, optimizing the therapeutic efficacy of ophthalmic medications.

Drug Classification:

Polyethylene Glycol and Propylene Glycol are classified as pharmaceutical excipients and vehicles commonly used in ophthalmic preparations. They are inert substances that enhance the stability, solubility, and bioavailability of active pharmaceutical ingredients in topical formulations.

Formulations:

AIT Pharmaceuticals Division offers Polyethylene Glycol and Propylene Glycol in the following formulation:

• Eye Drops: Each ml contains 4 mg of Polyethylene Glycol and 3 mg of Propylene Glycol in a sterile ophthalmic solution, packed in a convenient dropper bottle with a capacity of 15 ml.

Indications:

Polyethylene Glycol and Propylene Glycol eye drops are indicated for the relief of dry eye symptoms, including irritation, burning, itching, and discomfort associated with insufficient tear production or excessive tear evaporation. These eye drops provide lubrication and hydration to the ocular surface, promoting ocular comfort and clarity of vision.

Usage:

Administer one to two drops of Polyethylene Glycol and Propylene Glycol eye drops into the affected eye(s) as needed, or as directed by your healthcare provider. Tilt your head back, look upward, and gently pull down the lower eyelid to create a small pocket. Squeeze the dropper bottle to instill the prescribed number of drops into the eye(s) and then blink gently to distribute the medication evenly.

Dosage:

The recommended dosage of Polyethylene Glycol and Propylene Glycol eye drops may vary depending on the severity of dry eye symptoms and individual patient response. Use the medication as directed by your healthcare provider to achieve optimal therapeutic outcomes and alleviate discomfort effectively.

Side Effects:

Common side effects of Polyethylene Glycol and Propylene Glycol eye drops may include transient stinging or burning sensation upon instillation, temporary blurred vision, and mild eye irritation. Hypersensitivity reactions or allergic responses to the ingredients are rare but possible. If you experience any unexpected or severe side effects, discontinue use of the medication and consult your healthcare provider promptly.

Trust AIT Pharmaceuticals Division’s Polyethylene Glycol and Propylene Glycol eye drops to provide effective relief for dry eye symptoms and enhance ocular comfort. With our commitment to quality and patient care, we strive to improve the well-being of individuals and promote healthy vision for all.