Pharmacokinetics:

Olopatadine, the active ingredient in Olopatadine Ophthalmic Solution, is a selective histamine H1 receptor antagonist with potent anti-allergic properties. Upon topical application to the eye, Olopatadine is rapidly absorbed into the ocular tissues, where it exerts its therapeutic effects by blocking the action of histamine, a key mediator of allergic reactions. This results in the suppression of ocular itching, redness, and inflammation, providing rapid and sustained relief from allergic conjunctivitis symptoms.

Pharmacodynamics:

Olopatadine Ophthalmic Solution acts locally within the eye to alleviate the symptoms of allergic conjunctivitis, including itching, redness, tearing, and swelling. By antagonizing histamine receptors on ocular tissues, Olopatadine effectively inhibits the release of inflammatory mediators, thereby mitigating the allergic response and promoting ocular comfort and clarity.

Drug Classification:

Olopatadine Ophthalmic Solution belongs to the class of medications known as selective histamine H1 receptor antagonists. It is classified as an antiallergic agent, specifically indicated for the treatment of allergic conjunctivitis and related ocular allergies.

Formulations:

AIT Pharmaceuticals Division offers Olopatadine Ophthalmic Solution in the following formulations:

• Eye Drops: Each ml contains 1 mg or 2 mg of Olopatadine Hydrochloride (equivalent to Olopatadine base), formulated as a sterile ophthalmic solution for topical administration. The product is conveniently packaged in a dropper bottle with a capacity of 5 ml.

Indications:

Olopatadine Ophthalmic Solution is indicated for the temporary relief of ocular itching associated with allergic conjunctivitis, including symptoms such as redness, tearing, and swelling caused by environmental allergens such as pollen, dust, pet dander, and mold spores.

Usage:

To use Olopatadine Ophthalmic Solution, wash your hands thoroughly and tilt your head back. Gently pull down the lower eyelid to create a small pocket and hold the dropper bottle upside down. Instill one or two drops of the solution into the affected eye(s) while avoiding contact with the dropper tip to prevent contamination. Blink gently to distribute the medication evenly and repeat the process for the other eye if necessary.

Dosage:

The recommended dosage of Olopatadine Ophthalmic Solution is one to two drops instilled into the affected eye(s) twice daily, or as directed by your healthcare provider. Do not exceed the prescribed dosage, as excessive use may increase the risk of adverse effects.

Side Effects:

Common side effects of Olopatadine Ophthalmic Solution may include temporary stinging or burning sensation upon instillation, eye irritation, dryness, and blurred vision. Rare but serious side effects may include hypersensitivity reactions, eye pain, and corneal epithelial defects. If you experience any persistent or severe side effects, discontinue use of the medication and consult your healthcare provider promptly.

Trust AIT Pharmaceuticals Division’s Olopatadine Ophthalmic Solution to provide fast and effective relief from ocular allergy symptoms, ensuring clear and comfortable vision in the face of seasonal allergens. With our commitment to excellence and patient care, we are dedicated to enhancing the quality of life for individuals affected by ocular allergies.