Drug Class:

Cefpodoxime belongs to the third-generation cephalosporin class of antibiotics, renowned for their extended spectrum of activity against both Gram-positive and Gram-negative bacteria. With enhanced efficacy and broader coverage, third-generation cephalosporins like cefpodoxime are invaluable in the fight against bacterial infections.

Pharmacokinetics and Pharmacodynamics:

• Pharmacokinetics: Cefpodoxime is well absorbed after oral administration and achieves peak plasma concentrations within 2-3 hours. It is primarily excreted unchanged in the urine.
• Pharmacodynamics: Cefpodoxime exerts its bactericidal effects by inhibiting bacterial cell wall synthesis, leading to cell death. It demonstrates excellent activity against a wide range of Gram-positive and Gram-negative bacteria.

Formulation:

• Cefpodoxime 40mg/5ml Oral Suspension (DS): Each 5ml of oral suspension contains 40mg of Cefpodoxime, offering a convenient and palatable form for pediatric patients.
• Cefpodoxime 100mg Capsules: Each capsule contains 100mg of Cefpodoxime, providing a higher dosage option for pediatric and adult patients who may require stronger treatment.

Indications:

Cefpodoxime is indicated for the treatment of various bacterial infections, including:

• Upper respiratory tract infections (e.g., otitis media, sinusitis, pharyngitis)
• Lower respiratory tract infections (e.g., bronchitis, pneumonia)
• Skin and soft tissue infections
• Urinary tract infections

Side Effects:

• Common side effects of Cefpodoxime may include:
  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
• Serious adverse effects such as allergic reactions and pseudomembranous colitis may occur but are rare.

Usage:

• Cefpodoxime oral suspension and capsules are administered orally with or without food, as directed by a healthcare professional.
• It is crucial to complete the full course of treatment as prescribed, even if symptoms improve before completion, to ensure eradication of the infection and prevent recurrence.

Dosage:

• The recommended dosage of Cefpodoxime may vary depending on the type and severity of the infection, as well as patient factors such as age, weight, and renal function.
• The usual dosage for most infections is determined based on body weight and may range from 5mg/kg/day to 10mg/kg/day divided into two doses for pediatric patients and adults.

Packing Specifications:

• Cefpodoxime Oral Suspension (DS) is available in bottles containing 50ml, ensuring an ample supply for the prescribed course of treatment.
• Cefpodoxime Capsules are packed in blister packs containing 10 capsules, offering convenient and precise dosage administration.

Experience the effectiveness and reliability of AIT Pharmaceuticals Division’s Cefpodoxime Range in the treatment of bacterial infections. For further information and inquiries, please contact us.