Description

Drug Classification:

Cefadroxil belongs to the class of antibiotics known as cephalosporins, specifically classified as a first-generation cephalosporin. This class of antibiotics exhibits bactericidal activity against a broad spectrum of Gram-positive and Gram-negative bacteria.

Drug Forms:

• Cefadroxil Dispersible Tablets (DS):

• • • Strength: 90mg DS
    • Product Form: Dispersible tablets for oral suspension
    • Packing Specifications: Available in bottles containing 30ml of oral suspension

• Cefadroxil Capsules:

• • Strength: 400mg
  • Product Form: Hard gelatin capsules for oral administration
  • Packing Specifications: Available in blister packs of 10 capsules

Formulations:

• Cefadroxil DS: Each 5ml of oral suspension contains 90mg of cefadroxil.
• Cefadroxil Capsules: Each capsule contains 400mg of cefadroxil.

Indications:

Cefadroxil is indicated for the treatment of various bacterial infections caused by susceptible organisms, including:

• Skin and soft tissue infections
• Upper and lower respiratory tract infections
• Urinary tract infections
• Pharyngitis and tonsillitis
• Otitis media
• Impetigo

Usage:

• Cefadroxil tablets and dispersible tablets should be taken orally with or without food.
• Dispersible tablets should be reconstituted with water to form a suspension before administration, especially in pediatric patients.
• It is essential to complete the full course of treatment as prescribed by the healthcare provider, even if symptoms improve before the completion of the medication.

Dosage:

• The dosage of Cefadroxil varies depending on the type and severity of the infection, as well as the patient’s age and weight.
• The usual adult dosage for most infections ranges from 1 to 2 grams per day, administered in one or two divided doses.
• Pediatric dosages are determined based on the child’s weight and the severity of the infection.

Pharmacokinetics:

• Absorption: Cefadroxil is rapidly absorbed after oral administration, with peak plasma concentrations achieved within 1-2 hours.
• Distribution: The drug distributes widely into various body tissues and fluids, achieving therapeutic concentrations at the site of infection.
• Metabolism: Cefadroxil undergoes minimal metabolism in the body, with approximately 90% excreted unchanged in the urine.
• Elimination: The elimination half-life of cefadroxil is approximately 1.5-2 hours in adults with normal renal function.

Pharmacodynamics:

• Cefadroxil exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, leading to cell death.

Side Effects:

• Common side effects of Cefadroxil may include:

• • • Gastrointestinal disturbances, such as nausea, vomiting, diarrhea, and abdominal pain
    • Skin rash, itching, and urticaria

• Serious side effects such as pseudomembranous colitis and allergic reactions are rare but may occur.

Experience the efficacy and reliability of AIT Pharmaceuticals Division’s Cefadroxil Range in the treatment of bacterial infections. For more information, please contact us. We are dedicated to providing high-quality pharmaceutical products to healthcare professionals worldwide.