Description

Formulations:

• Ceftriaxone Sodium Vial: Available in multiple strengths, including 250mg, 500mg, 1000mg, and 2000mg, our vials contain a sterile powder for reconstitution, providing convenient and flexible dosing options.

Indications:

• Our Ceftriaxone Sodium Vial is indicated for the treatment of various infections caused by susceptible organisms, including:
  • Lower respiratory tract infections, such as pneumonia and bronchitis
  • Urinary tract infections, including cystitis and pyelonephritis
  • Skin and soft tissue infections, including cellulitis and wound infections
  • Intra-abdominal infections, such as peritonitis and cholecystitis
  • Bone and joint infections, including osteomyelitis
  • Meningitis
  • Gonorrhea and pelvic inflammatory disease (PID)

Pharmacokinetics:

• Absorption: Ceftriaxone is administered parenterally and achieves high plasma concentrations after intramuscular or intravenous injection.
• Distribution: The drug distributes widely into various body tissues and fluids, including the lungs, kidneys, liver, and cerebrospinal fluid.
• Metabolism: Ceftriaxone undergoes minimal metabolism in the liver, with approximately 33-67% excreted unchanged in the urine.
• Elimination: The elimination half-life of ceftriaxone is approximately 5-9 hours in adults, allowing for once-daily dosing in most cases.

Pharmacodynamics:

• Ceftriaxone exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, leading to cell lysis and death.

Usage:

• Our Ceftriaxone Sodium Vial is intended for intravenous or intramuscular administration by healthcare professionals trained in the proper handling and reconstitution of injectable medications.

Dosage:

• The dosage of Ceftriaxone Sodium varies depending on the type and severity of the infection, as well as the patient’s age, weight, and renal function.
• Dosage adjustments may be necessary in patients with impaired renal function to prevent drug accumulation and toxicity.

Side Effects:

• Common side effects of Ceftriaxone Sodium may include:
  • Diarrhea
  • Nausea and vomiting
  • Injection site reactions, such as pain and swelling
  • Hypersensitivity reactions, including rash and itching
• Serious side effects such as anaphylaxis, Clostridium difficile-associated diarrhea, and superinfections may occur, although they are rare.

Experience the efficacy and reliability of AIT Pharmaceuticals Division’s Ceftriaxone Sodium Vial Range in the treatment of bacterial infections. For more information, please contact us.