Description

Drug Class:

Cefuroxime belongs to the class of antibiotics known as second-generation cephalosporins. These antibiotics are renowned for their broad spectrum of activity against both Gram-positive and Gram-negative bacteria.

Formulation:

• Cefuroxime 125mg/5ml Oral Suspension (DS): Each 5ml of oral suspension contains 125mg of Cefuroxime, providing a convenient and palatable form for pediatric patients.
• Cefuroxime 250mg/5ml Oral Suspension (DS): Each 5ml of oral suspension contains 250mg of Cefuroxime, offering a higher dosage option for pediatric patients and adults who may require a higher strength.

Pharmacokinetics and Pharmacodynamics:

• Pharmacokinetics: Cefuroxime is well absorbed after oral administration and achieves peak plasma concentrations within 2-3 hours. It is primarily eliminated unchanged in the urine.
• Pharmacodynamics: Cefuroxime exerts its bactericidal effects by inhibiting bacterial cell wall synthesis, leading to cell death. It demonstrates excellent activity against a wide range of Gram-positive and Gram-negative bacteria.

Indications:

Cefuroxime is indicated for the treatment of various bacterial infections, including:

• Upper respiratory tract infections (e.g., otitis media, sinusitis, pharyngitis)
• Lower respiratory tract infections (e.g., bronchitis, pneumonia)
• Skin and soft tissue infections
• Urinary tract infections
• Gonorrhea
• Lyme disease

Side Effects:

• Common side effects of Cefuroxime may include:
  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
• Serious adverse effects such as allergic reactions and pseudomembranous colitis may occur but are rare.

Usage:

• Cefuroxime oral suspension is administered orally with or without food, as directed by a healthcare professional.
• It is essential to complete the full course of treatment as prescribed, even if symptoms improve before completion, to ensure eradication of the infection and prevent recurrence.

Dosage:

• The recommended dosage of Cefuroxime may vary depending on the type and severity of the infection, as well as patient factors such as age, weight, and renal function.
• The usual dosage for most infections is determined based on body weight and may range from 125mg to 500mg twice daily for pediatric patients and adults.

Packing Specifications:

• Cefuroxime Oral Suspension (DS) is available in bottles containing 50ml, ensuring an ample supply for the prescribed course of treatment.

Experience the effectiveness and reliability of AIT Pharmaceuticals Division’s Cefuroxime Range in the treatment of bacterial infections. For further information and inquiries, please contact us.