Description

Drug Classification:

Cilostazol Tablets belong to the class of medications known as platelet aggregation inhibitors. These tablets work by inhibiting specific enzymes in the body, thereby preventing platelets from sticking together and forming blood clots. As a result, Cilostazol helps improve blood flow and circulation, particularly in the legs.

Formulations:

• Cilostazol Tablets:
  • Strength: Available in two strengths – 50mg and 100mg tablets.
  • Product Form: Easy-to-swallow oral tablets for convenient administration.
  • Packing Specifications: Packaged in blister packs containing 30 tablets each, ensuring freshness and potency.

Indications:

Cilostazol Tablets are indicated for the following conditions:

• Intermittent Claudication: Cilostazol is used to treat intermittent claudication, a condition characterized by pain, cramping, or weakness in the legs during physical activity due to poor blood flow.
• Peripheral Arterial Disease (PAD): Cilostazol is prescribed to improve walking distance and reduce symptoms in patients with peripheral arterial disease, a condition caused by narrowing of the arteries in the legs.
• Prevention of Secondary Stroke: Cilostazol may be used in combination with aspirin to reduce the risk of recurrent stroke in patients who have experienced an ischemic stroke or transient ischemic attack (TIA).

Usage:

• Cilostazol Tablets should be taken orally, usually twice daily, preferably one hour before or two hours after meals.
• It is essential to follow the prescribed dosage and schedule recommended by your healthcare provider.
• Do not stop taking Cilostazol without consulting your doctor, as sudden discontinuation may lead to worsening of symptoms.

Dosage:

• The recommended starting dose of Cilostazol is 100mg twice daily.
• Based on individual response and tolerability, the dosage may be adjusted by your healthcare provider.
• Elderly patients or those with liver or kidney impairment may require lower doses of Cilostazol.

Pharmacokinetics:

• Cilostazol is rapidly absorbed after oral administration, with peak plasma concentrations reached within 2-3 hours.
• The drug undergoes extensive metabolism in the liver, primarily by the cytochrome P450 enzyme system, to form active metabolites.
• The elimination half-life of Cilostazol and its metabolites is approximately 11-13 hours.

Pharmacodynamics:

• Cilostazol exerts its pharmacological effects by inhibiting phosphodiesterase III (PDE3) enzymes, leading to increased levels of cyclic adenosine monophosphate (cAMP) in platelets and blood vessels.
• Elevated cAMP levels in platelets inhibit platelet aggregation and thrombus formation, while vasodilation occurs in blood vessels, improving blood flow and circulation.

Side Effects:

• Common side effects of Cilostazol may include headache, diarrhea, palpitations, dizziness, and abnormal stools.
• Serious side effects such as bleeding, allergic reactions, and worsening heart conditions are rare but may occur.
• Contact your healthcare provider immediately if you experience severe or persistent side effects while taking Cilostazol.

Experience the therapeutic benefits of Cilostazol Tablets from AIT Pharmaceuticals Division. Trust in our commitment to quality, safety, and efficacy as we strive to improve patient outcomes and enhance quality of life. For more information, please visit our website or consult your healthcare provider.