Description

Drug Classification:

Desloratadine belongs to the class of drugs known as second-generation antihistamines. It works by selectively antagonizing the histamine H1 receptor, thereby blocking the action of histamine and alleviating symptoms associated with allergic reactions.

Formulations:

• Desloratadine Tablets:
  • Strength: Each tablet contains 5 mg of Desloratadine.
  • Product Form: Oral tablets for convenient administration.
  • Packing Specifications: Packaged in blister packs containing 10 tablets each.

Indications:

Desloratadine Tablets are indicated for the relief of symptoms associated with allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives) in adults and pediatric patients aged 6 months and older.

Usage:

• Desloratadine Tablets should be taken orally with or without food, as directed by a healthcare professional.
• For allergic rhinitis, the medication can be taken once daily to alleviate symptoms such as sneezing, itching, runny nose, and nasal congestion.
• For chronic idiopathic urticaria, Desloratadine Tablets are typically taken once daily to reduce the occurrence and severity of hives and associated itching.

Dosage:

• For adults and children aged 12 years and older: The recommended dosage is 5mg once daily.
• For pediatric patients aged 6 months to 11 years: The dosage should be determined based on body weight, as recommended by a healthcare provider.

Pharmacokinetics:

• Desloratadine is rapidly absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations achieved within 3 hours.
• The drug undergoes extensive hepatic metabolism to form its active metabolite, 3-hydroxy desloratadine.
• Desloratadine and its metabolite are primarily eliminated via renal excretion, with elimination half-lives ranging from 27 to 36 hours.

Pharmacodynamics:

• Desloratadine exerts its pharmacological effects by selectively blocking the histamine H1 receptor, thereby inhibiting the action of histamine on target tissues.
• By antagonizing histamine-mediated responses, Desloratadine reduces the symptoms of allergic rhinitis and chronic idiopathic urticaria, including itching, sneezing, nasal congestion, and hives.

Side Effects:

• Common side effects of Desloratadine Tablets may include headache, fatigue, dry mouth, and gastrointestinal disturbances.
• Rare but serious side effects may include allergic reactions, palpitations, and urinary retention.
• Patients should be monitored for any adverse reactions during treatment with Desloratadine, and healthcare providers should be informed of any concerning symptoms.

Experience the relief provided by AIT Pharmaceuticals Division’s Desloratadine Tablets for allergic rhinitis and chronic idiopathic urticaria. For more information, please contact us. We are dedicated to providing effective pharmaceutical solutions to healthcare professionals worldwide.