Formulations:

• Diacerein Capsules:
  • Strength: Each capsule contains 50mg of Diacerein
  • Product Form: Oral capsules for convenient administration
  • Packing Specifications: Available in packs of 30 capsules.

Indications:

Diacerein Capsules are indicated for the treatment of osteoarthritis, a degenerative joint disease characterized by pain, stiffness, and decreased mobility. It helps alleviate symptoms associated with osteoarthritis, including joint pain and inflammation, and may also slow down the progression of the disease.

Usage:

• Diacerein Capsules should be taken orally with water, preferably after meals to minimize gastrointestinal side effects.
• The medication is typically used as a long-term treatment to provide sustained relief from osteoarthritis symptoms and improve joint function.
• It is essential to follow the instructions provided by a healthcare professional regarding the duration of treatment and monitoring of response.

Dosage:

• The recommended dosage of Diacerein Capsules is usually one capsule (50mg) taken once daily.
• Dosage adjustments may be made based on individual patient response and tolerability, as directed by a healthcare professional.
• It may take several weeks to experience the full therapeutic effects of Diacerein, so consistent use is essential for optimal outcomes.

Pharmacokinetics:

• Absorption: Diacerein is well absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations achieved within 2 to 3 hours.
• Distribution: The drug is distributed extensively throughout the body, including to the joints affected by osteoarthritis.
• Metabolism: Diacerein undergoes extensive metabolism in the liver, primarily via glucuronidation, to form inactive metabolites.
• Elimination: The elimination half-life of Diacerein is relatively long, ranging from 3 to 4 hours, with the majority of the drug and its metabolites excreted in the urine and feces.

Pharmacodynamics:

• Diacerein exerts its therapeutic effects by inhibiting the production of pro-inflammatory cytokines and enzymes involved in cartilage degradation, such as interleukin-1 beta and matrix metalloproteinases. By reducing inflammation and slowing down joint degeneration, Diacerein helps alleviate symptoms and improve joint function in osteoarthritis patients.

Side Effects:

• Common side effects of Diacerein may include gastrointestinal disturbances such as diarrhea, abdominal pain, and nausea.
• Rare but serious side effects may include liver toxicity, skin reactions, and allergic reactions.
• It is important to consult a healthcare professional if any adverse reactions occur during treatment with Diacerein.

Experience the relief provided by AIT Pharmaceuticals Division’s Diacerein Capsules for osteoarthritis management. For more information, please contact us. We are committed to providing effective pharmaceutical solutions to healthcare professionals worldwide.