Description
Drug Classification:
Ebastine belongs to the class of drugs known as second-generation antihistamines. It exerts its therapeutic effects by selectively antagonizing the histamine H1 receptor, thereby blocking the action of histamine and reducing the symptoms associated with allergic reactions.
Formulations:
- Ebastine Tablets:
- Strength: Each tablet contains 10mg of Ebastine.
- Product Form: Oral tablets for convenient administration.
- Packing Specifications: Packaged in blister packs containing 10 tablets each.
Indications:
Ebastine Tablets are indicated for the relief of symptoms associated with allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives) in adults and pediatric patients aged 12 years and older.
Usage:
- Ebastine Tablets should be taken orally with or without food, as directed by a healthcare professional.
- For allergic rhinitis, the medication can be taken once daily to alleviate symptoms such as sneezing, itching, runny nose, and nasal congestion.
- For chronic idiopathic urticaria, Ebastine Tablets are typically taken once daily to reduce the occurrence and severity of hives and associated itching.
Dosage:
- For adults and children aged 12 years and older: The recommended dosage is 10mg once daily.
- Dosage adjustment may be necessary for elderly patients or those with hepatic impairment, as Ebastine undergoes hepatic metabolism.
Pharmacokinetics:
- Ebastine is rapidly absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations achieved within 1 to 2 hours.
- The drug undergoes extensive first-pass metabolism in the liver to form its active metabolite, carebastine.
- Ebastine and carebastine are primarily excreted in the feces and urine, with elimination half-lives ranging from 10 to 17 hours.
Pharmacodynamics:
- Ebastine exerts its pharmacological effects by selectively blocking the histamine H1 receptor, thereby preventing the action of histamine on target tissues.
- By inhibiting histamine-mediated responses, Ebastine reduces the symptoms of allergic rhinitis and chronic idiopathic urticaria, including itching, sneezing, nasal congestion, and hives.
Side Effects:
- Common side effects of Ebastine Tablets may include headache, drowsiness, dry mouth, and gastrointestinal disturbances.
- Rare but serious side effects may include allergic reactions, palpitations, and urinary retention.
- Patients should be monitored for any adverse reactions during treatment with Ebastine, and healthcare providers should be informed of any concerning symptoms.
Experience the relief provided by AIT Pharmaceuticals Division’s Ebastine Tablets for allergic rhinitis and chronic idiopathic urticaria. For more information, please contact us. We are committed to providing effective pharmaceutical solutions to healthcare professionals worldwide.
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