Formulations:

Etoricoxib Tablets:

• • Strength: Available in 60mg tablets
  • Product Form: Oral tablets for convenient administration
  • Packing Specifications: Each pack contains 10 tablets

Indications:

Etoricoxib is indicated for the treatment of various painful and inflammatory conditions, including:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Acute gouty arthritis
• Chronic musculoskeletal pain
• Acute pain (including postoperative dental pain)

Usage:

• Etoricoxib tablets should be taken orally with a full glass of water, preferably with or after food to minimize gastrointestinal irritation.
• The duration of treatment and dosage regimen may vary depending on the specific condition being treated, the patient’s response to therapy, and other individual factors.

Dosage:

• The recommended dosage of Etoricoxib for most indications is 60 mg once daily.
• Dosage adjustments may be necessary in elderly patients, patients with hepatic impairment, or those with renal impairment.
• The maximum daily dose should not exceed 60 mg.

Pharmacokinetics:

• Absorption: Etoricoxib is well absorbed after oral administration, with peak plasma concentrations achieved within 1 to 2 hours.
• Distribution: The drug is highly protein-bound (more than 90%) and is distributed extensively throughout the body.
• Metabolism: Etoricoxib undergoes hepatic metabolism primarily via the cytochrome P450 enzyme CYP3A4.
• Elimination: The elimination half-life of Etoricoxib is approximately 22 hours. It is primarily excreted in the feces and urine, mainly as metabolites.

Pharmacodynamics:

Etoricoxib selectively inhibits COX-2, leading to suppression of prostaglandin synthesis. By reducing inflammation and pain, it provides relief to patients suffering from various musculoskeletal conditions.

Side Effects:

Common side effects of Etoricoxib may include:

• • Gastrointestinal disturbances (e.g., dyspepsia, abdominal pain)
  • Headache
  • Dizziness
  • Edema
  • Hypertension
    Serious adverse reactions such as gastrointestinal bleeding, ulceration, and cardiovascular events may occur, particularly with long-term use or high doses.

Experience the efficacy and safety of AIT Pharmaceuticals Division’s Etoricoxib Range in the management of pain and inflammation. For more information, please contact us. We are committed to providing high-quality pharmaceutical products to healthcare professionals worldwide.