Description

Drug Classification:

Fexofenadine HCl is classified as a second-generation antihistamine, while Pseudoephedrine HCl is classified as a sympathomimetic amine. Together, these medications work synergistically to alleviate allergic symptoms and nasal congestion.

Formulations:

• Fexofenadine HCl + Pseudoephedrine HCl Tablets:
  • Strength: Each tablet contains Fexofenadine HCl 120mg and Pseudoephedrine HCl 60mg.
  • Product Form: Oral tablets for easy administration.
  • Packing Specifications: Packaged in blister packs containing 10 tablets each.

Indications:

Fexofenadine HCl + Pseudoephedrine HCl Tablets are indicated for the relief of symptoms associated with seasonal allergic rhinitis (hay fever) and nasal congestion. These symptoms may include sneezing, runny or itchy nose, itchy or watery eyes, nasal congestion, and sinus pressure.

Usage:

• Fexofenadine HCl + Pseudoephedrine HCl Tablets should be taken orally with water, preferably with or without food.
• The medication is typically used on an as-needed basis to alleviate allergy symptoms and nasal congestion promptly.
• It is essential to follow the instructions provided by a healthcare professional regarding the timing and frequency of dosing.

Dosage:

• The recommended dosage of Fexofenadine HCl + Pseudoephedrine HCl Tablets is one tablet every 12 hours.
• It is important not to exceed the recommended dose or frequency of administration to avoid adverse effects and potential drug interactions.
• The duration of treatment may vary depending on the severity of symptoms and the patient’s response to therapy.

Pharmacokinetics:

• The pharmacokinetics of Fexofenadine HCl and Pseudoephedrine HCl are well-characterized individually.
• Fexofenadine is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations achieved within 2 to 3 hours. It undergoes minimal metabolism and is primarily excreted unchanged in the urine.
• Pseudoephedrine is also rapidly absorbed, with peak plasma concentrations reached within 2 hours. It is extensively metabolized in the liver, primarily via oxidation and conjugation, and excreted in the urine.

Pharmacodynamics:

• Fexofenadine HCl antagonizes the action of histamine at H1 receptors, thereby preventing allergic symptoms such as itching, sneezing, and runny nose.
• Pseudoephedrine HCl acts as a sympathomimetic agent, stimulating alpha-adrenergic receptors to produce vasoconstriction in the nasal mucosa, leading to reduced nasal congestion.

Side Effects:

• Common side effects of Fexofenadine HCl + Pseudoephedrine HCl Tablets may include headache, dizziness, insomnia, dry mouth, and gastrointestinal upset.
• Rare but serious side effects may include palpitations, hypertension, urinary retention, and allergic reactions.
• It is important to consult a healthcare professional if any adverse reactions occur during treatment with Fexofenadine HCl + Pseudoephedrine HCl Tablets.

Experience the relief provided by AIT Pharmaceuticals Division’s Fexofenadine HCl + Pseudoephedrine HCl Tablets for allergy and congestion relief. For more information, please contact us. We are dedicated to providing effective pharmaceutical solutions to healthcare professionals worldwide.