Description

Drug Class:

Levofloxacin belongs to the fluoroquinolone class of antibiotics, renowned for their broad-spectrum activity against both Gram-positive and Gram-negative bacteria. With its excellent tissue penetration and bactericidal properties, levofloxacin is an essential tool in the fight against bacterial infections.

Pharmacokinetics and Pharmacodynamics:

• Pharmacokinetics: Levofloxacin is well absorbed after oral administration and achieves peak plasma concentrations within 1-2 hours. It is primarily excreted unchanged in the urine.
• Pharmacodynamics: Levofloxacin exerts its bactericidal effects by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes involved in DNA replication and repair.

Formulation:

• Levofloxacin 125mg/5ml Oral Suspension (DS): Each 5ml of oral suspension contains 125mg of Levofloxacin, providing a convenient and palatable form for pediatric patients.
• Levofloxacin Tablets: Available in strengths of 250mg, 500mg, and 750mg, our tablets offer precise dosage options for both adult and pediatric patients.
• Levofloxacin 500mg Injection (Gen. Ifusion): Our injection formulation provides a rapid and effective means of delivering levofloxacin for patients who may require parenteral administration.

Indications:

Levofloxacin is indicated for the treatment of various bacterial infections, including:

• Respiratory tract infections (e.g., pneumonia, bronchitis)
• Urinary tract infections (e.g., cystitis, pyelonephritis)
• Skin and soft tissue infections
• Sexually transmitted infections (e.g., gonorrhea)
• Intra-abdominal infections
• Acute bacterial sinusitis

Side Effects:

• Common side effects of Levofloxacin may include:
  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Insomnia
• Serious adverse effects such as tendon rupture, peripheral neuropathy, and allergic reactions may occur but are rare.

Usage:

• Levofloxacin oral suspension, tablets, and injection are administered orally or intravenously, as directed by a healthcare professional.
• It is essential to follow the prescribed dosage regimen and complete the full course of treatment, even if symptoms improve before completion, to ensure effective eradication of the infection.

Dosage:

• The recommended dosage of Levofloxacin may vary depending on the type and severity of the infection, as well as patient factors such as age, weight, and renal function.
• Dosage adjustments may be necessary in patients with impaired renal function to prevent drug accumulation and potential adverse effects.

Packing Specifications:

• Levofloxacin Oral Suspension (DS) is available in bottles containing 60ml, ensuring an ample supply for the prescribed course of treatment.
• Levofloxacin Tablets are packed in blister packs containing 10 tablets, offering convenient and precise dosage administration.
• Levofloxacin Injection (Gen. Ifusion) is available in single-use vials, providing a sterile and ready-to-use solution for intravenous administration.

Experience the effectiveness and reliability of AIT Pharmaceuticals Division’s Levofloxacin Range in the treatment of bacterial infections. For further information and inquiries, please contact us.