Description

Drug Classification:

Loratadine belongs to a class of drugs known as second-generation antihistamines. It selectively antagonizes the histamine H1 receptor, thereby reducing the symptoms associated with allergic reactions, such as sneezing, itching, watery eyes, and runny nose.

Formulations:

• Loratadine Tablets:
  • Strength: Available in 10mg tablets.
  • Product Form: Oral tablets for convenient administration.
  • Packing Specifications: Packaged in blister packs containing 10 tablets each.

Indications:

Loratadine Tablets are indicated for the relief of symptoms associated with allergic rhinitis (hay fever) and for the treatment of chronic idiopathic urticaria (hives) in adults and pediatric patients aged 6 years and older.

Usage:

• Loratadine Tablets should be taken orally with or without food, as directed by a healthcare professional.
• For allergic rhinitis, the medication can be taken once daily, preferably in the evening, to alleviate symptoms associated with seasonal or perennial allergies.
• For chronic idiopathic urticaria, Loratadine Tablets are typically taken once daily to reduce the occurrence and severity of hives.

Dosage:

• For adults and children aged 12 years and older: 10mg once daily.
• For pediatric patients aged 6 to 11 years: 5mg (half tablet) once daily.

Pharmacokinetics:

• Loratadine is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations achieved within 1 to 2 hours following oral administration.
• The drug undergoes extensive first-pass metabolism in the liver to form its active metabolite, desloratadine.
• Loratadine and desloratadine are primarily excreted in the urine, with elimination half-lives ranging from 3 to 20 hours.

Pharmacodynamics:

• Loratadine exerts its pharmacological effects by selectively blocking the histamine H1 receptor, thereby preventing the action of histamine on target tissues.
• By inhibiting the effects of histamine, Loratadine reduces the symptoms of allergic rhinitis and chronic idiopathic urticaria, including nasal congestion, itching, sneezing, and hives.

Side Effects:

• Common side effects of Loratadine Tablets may include headache, dry mouth, fatigue, and gastrointestinal disturbances.
• Rare but serious side effects may include allergic reactions, palpitations, and urinary retention.
• Patients should be monitored for any adverse reactions during treatment with Loratadine, and healthcare providers should be informed of any concerning symptoms.

Experience the relief provided by AIT Pharmaceuticals Division’s Loratadine Tablets for allergic rhinitis and chronic idiopathic urticaria. For more information, please contact us. We are committed to providing effective pharmaceutical solutions to healthcare professionals worldwide.