Description

Pharmacokinetics:

Pantoprazole Na is a proton pump inhibitor (PPI) that is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations achieved within 2 hours of oral administration. It undergoes extensive hepatic metabolism, primarily via the cytochrome P450 enzyme system, and is excreted primarily in the urine. Pantoprazole Na has a half-life of approximately 1 hour and exhibits nonlinear pharmacokinetics at higher doses.

Pharmacodynamics:

As a PPI, Pantoprazole Na works by irreversibly binding to and inhibiting the hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) enzyme system on the surface of gastric parietal cells. This inhibits the secretion of gastric acid into the stomach lumen, resulting in reduced acidity and suppression of acid-related symptoms such as heartburn and acid reflux.

Drug Classification:

Pantoprazole Na is classified as a proton pump inhibitor (PPI).

Formulations:

• Pantoprazole Na 40mg tablets (14’s)
• Pantoprazole Na 40mg injection (1’s)

Indications:

AIT’s Pantoprazole Na Range is indicated for the short-term treatment of erosive esophagitis associated with GERD, maintenance of healing of erosive esophagitis, treatment of symptomatic GERD, and treatment of pathological hypersecretory conditions such as Zollinger-Ellison syndrome.

Usage:

For oral tablets, swallow whole with water, with or without food, as directed by a healthcare professional. For intravenous injection, administer under medical supervision according to the prescribed dosage regimen.

Dosage:

The recommended dosage of Pantoprazole Na varies depending on the indication and severity of the condition being treated. Consult a healthcare provider for personalized dosing instructions. Do not exceed the maximum recommended daily dose to avoid the risk of adverse effects.

Side Effects:

Common side effects of Pantoprazole Na may include headache, diarrhea, abdominal pain, nausea, and vomiting. Rare but serious side effects may include allergic reactions, severe skin reactions, and an increased risk of bone fractures. Promptly seek medical attention if any adverse reactions occur.

Experience relief from acid-related disorders with AIT Pharmaceuticals Division’s Pantoprazole Na Range. Trust in our commitment to quality and efficacy for superior symptom management and gastrointestinal health.