Description

Pharmacokinetics:

Paracetamol, also known as acetaminophen, is rapidly and completely absorbed from the gastrointestinal tract, with peak plasma concentrations achieved within 30 to 60 minutes following oral administration. It is primarily metabolized in the liver and excreted predominantly in the urine as glucuronide and sulfate conjugates. Paracetamol exhibits minimal plasma protein binding and has a half-life of approximately 2 to 3 hours in adults.

Pharmacodynamics:

Paracetamol exerts its analgesic and antipyretic effects by inhibiting the synthesis of prostaglandins in the central nervous system, thereby reducing pain and fever. It acts centrally on the hypothalamic heat-regulating centers to lower body temperature, while its precise mechanism of action in pain relief is not fully understood. Paracetamol is considered a non-opioid analgesic and antipyretic agent.

Drug Classification:

Paracetamol is classified as a non-opioid analgesic and antipyretic agent.

Formulations:

• Paracetamol 500mg tablets (100’s)
• Paracetamol 500mg Gen Infusion 100ml

Indications:

AIT’s Paracetamol Range is indicated for the relief of mild to moderate pain, including headache, toothache, muscle ache, backache, and menstrual cramps. It is also indicated for the reduction of fever associated with various conditions, such as colds, flu, and viral infections.

Usage:

For oral tablets, swallow whole with water, with or without food, as directed by a healthcare professional. For intravenous infusion, administer under medical supervision according to the prescribed dosage regimen.

Dosage:

The recommended dosage of Paracetamol varies depending on the age, weight, and medical condition of the patient. Consult a healthcare provider for personalized dosing instructions. Do not exceed the maximum daily dose to avoid the risk of overdose and adverse effects.

Side Effects:

Common side effects of Paracetamol may include nausea, vomiting, abdominal pain, and allergic reactions such as skin rash or itching. In rare cases, overdose of Paracetamol can lead to liver damage and failure. Promptly seek medical attention if any adverse reactions occur.

Experience fast and effective relief from pain and fever with AIT Pharmaceuticals Division’s Paracetamol Range. Trust in our commitment to quality and efficacy for superior symptom management and well-being.