Description

Formulations:

• Piroxicam Liquid Ampule:
  • Strength: Each ampule contains 20 mg of Piroxicam
  • Product Form: Liquid solution for injection
  • Packing Specifications: Each pack contains 5 ampules for convenient administration

Indications:

Piroxicam is indicated for the treatment of various inflammatory and painful conditions, including:

• Rheumatoid arthritis
• Osteoarthritis
• Acute gout
• Ankylosing spondylitis
• Soft tissue injuries and musculoskeletal disorders
• Postoperative pain and inflammation

Usage:

• Piroxicam Liquid Ampules are intended for intravenous or intramuscular administration by healthcare professionals.
• It is recommended for short-term use to manage acute symptoms of inflammation and pain.
• The choice of route of administration and dosage regimen should be individualized based on the patient’s condition, severity of symptoms, and response to treatment.

Dosage:

• The recommended dosage of Piroxicam typically ranges from 20 to 40 mg per day, divided into one or two doses.
• For acute conditions, an initial higher dose may be administered followed by a lower maintenance dose.
• Dosage adjustments may be necessary in elderly patients, patients with renal or hepatic impairment, and those at risk of gastrointestinal adverse effects.

Pharmacokinetics:

• Absorption: Piroxicam is well absorbed following oral or parenteral administration, with peak plasma concentrations achieved within 2 to 4 hours.
• Distribution: Piroxicam has a large volume of distribution and is highly protein-bound.
• Metabolism: Piroxicam undergoes extensive hepatic metabolism, primarily via oxidation and conjugation, resulting in inactive metabolites.
• Elimination: The elimination half-life of Piroxicam is approximately 30 to 50 hours, with the majority of the drug excreted renally as metabolites.

Pharmacodynamics:

• Piroxicam exerts its anti-inflammatory, analgesic, and antipyretic effects by inhibiting the synthesis of prostaglandins, thereby reducing pain, inflammation, and fever.

Side Effects:

• Common side effects of Piroxicam may include:
  • Gastrointestinal disturbances such as dyspepsia, abdominal pain, and gastritis
  • Renal impairment, including fluid retention and edema
  • Hematological effects such as anemia and thrombocytopenia
  • Skin reactions, including rash and photosensitivity
• Serious adverse reactions such as gastrointestinal bleeding, renal failure, and hypersensitivity reactions may occur, particularly with prolonged use or in patients with pre-existing conditions.

Experience the efficacy and reliability of AIT Pharmaceuticals Division’s Piroxicam Range for effective pain and inflammation management. For more information, please contact us. We are committed to providing superior pharmaceutical solutions to healthcare professionals worldwide.