Formulations:

• Piroxicam BCD Tablets:
  • Strength: Available in 20mg tablets
  • Product Form: Oral tablets for convenient administration
  • Packing Specifications: Each pack contains 20 tablets

Indications:

Piroxicam BCD is indicated for the relief of signs and symptoms of:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Acute musculoskeletal disorders
• Acute gout

Usage:

• Piroxicam BCD tablets should be taken orally with a full glass of water, preferably with or after food to minimize gastrointestinal irritation.
• The dosage and duration of treatment should be individualized based on the patient’s response to therapy, severity of symptoms, and other relevant factors.

Dosage:

• The recommended dosage of Piroxicam BCD for most indications is 20mg once daily.
• In some cases, a higher initial dose of up to 40mg daily may be prescribed for more severe symptoms.
• Dosage adjustments may be necessary in elderly patients, patients with renal impairment, or those with hepatic impairment.

Pharmacokinetics:

• Absorption: Piroxicam is well absorbed after oral administration, with peak plasma concentrations achieved within 3 to 5 hours.
• Distribution: The drug is extensively protein-bound and widely distributed throughout the body, including synovial fluid.
• Metabolism: Piroxicam undergoes hepatic metabolism via cytochrome P450 enzymes, primarily CYP2C9.
• Elimination: The elimination half-life of Piroxicam is approximately 50 hours. It is primarily excreted in the urine and feces, mainly as metabolites.

Pharmacodynamics:

• Piroxicam exerts its anti-inflammatory, analgesic, and antipyretic effects by inhibiting the enzyme COX, thereby reducing the production of prostaglandins involved in the inflammatory process.

Side Effects:

• Common side effects of Piroxicam BCD may include:
  • Gastrointestinal disturbances (e.g., dyspepsia, abdominal pain)
  • Headache
  • Dizziness
  • Edema
  • Hypertension
• Serious adverse reactions such as gastrointestinal bleeding, ulceration, and cardiovascular events may occur, particularly with long-term use or high doses.

Experience the efficacy and safety of AIT Pharmaceuticals Division’s Piroxicam BCD Range in the management of pain and inflammation. For more information, please contact us. We are committed to providing high-quality pharmaceutical products to healthcare professionals worldwide.