Description

Drug Classification:

Risperidone belongs to the class of medications known as atypical antipsychotics. It exerts its therapeutic effects by antagonizing dopamine and serotonin receptors in the brain, thereby alleviating symptoms associated with psychotic disorders.

Formulations:

• Risperidone Tablets:
  • Strength: Available in 1mg, 2mg, 3mg, and 4mg tablets.
  • Product Form: Oral tablets for convenient administration.
  • Packing Specs: Each pack contains 20 tablets.

Indications:

Risperidone Tablets are indicated for the treatment of various psychiatric disorders, including:

• Schizophrenia: Management of symptoms such as hallucinations, delusions, disorganized thinking, and emotional disturbances associated with schizophrenia.
• Bipolar Disorder: Treatment of acute manic or mixed episodes and maintenance therapy to prevent recurrence of manic episodes in patients with bipolar I disorder.
• Irritability Associated with Autism Spectrum Disorder: Reduction of irritability and aggression in pediatric patients aged 5 to 16 years with autism spectrum disorder.

Usage:

• Risperidone Tablets should be taken orally once daily, with or without food, as directed by a healthcare provider.
• It is important to adhere to the prescribed dosage and treatment regimen to achieve optimal therapeutic outcomes.
• Dosage adjustments should be made cautiously under the supervision of a healthcare professional based on individual response and tolerability.

Dosage:

• The recommended initial dosage of Risperidone for schizophrenia in adults is 1mg to 2mg once daily. The dosage may be titrated gradually based on response, up to a maximum of 8mg per day.
• For the treatment of bipolar disorder, the initial dosage ranges from 2mg to 3 mg once daily. The maintenance dosage typically ranges from 1mg to 6 mg per day.
• Pediatric patients with autism spectrum disorder may initiate treatment with a dosage of 0.25mg to 0.5mg once daily, titrated gradually up to a maximum of 3.5mg per day based on response and tolerability.

Pharmacokinetics:

• Risperidone is rapidly absorbed after oral administration, with peak plasma concentrations achieved within 1 to 2 hours.
• It undergoes extensive hepatic metabolism via the CYP2D6 enzyme system, yielding an active metabolite, 9-hydroxyrisperidone.
• The elimination half-life of risperidone and its metabolite ranges from 20 to 30 hours, allowing for once-daily dosing.

Pharmacodynamics:

• Risperidone exerts its pharmacological effects primarily through antagonism of dopamine D2 and serotonin 5-HT2A receptors in the central nervous system.
• By modulating dopaminergic and serotonergic neurotransmission, risperidone effectively mitigates positive and negative symptoms associated with schizophrenia and bipolar disorder.

Side Effects:

• Common side effects of Risperidone Tablets may include drowsiness, dizziness, weight gain, constipation, and dry mouth.
• Some individuals may experience extrapyramidal symptoms such as tremor, akathisia, and dystonia, particularly at higher dosages.
• Metabolic adverse effects such as hyperglycemia, dyslipidemia, and weight gain may occur, necessitating regular monitoring of metabolic parameters.
• It is essential to report any unusual or severe side effects to a healthcare provider promptly.

Trust in the efficacy and safety of Risperidone Tablets from AIT Pharmaceuticals Division. We are dedicated to supporting individuals with psychiatric disorders and providing them with the treatment they need to lead fulfilling lives. For more information, please visit our website or consult your healthcare provider.